Over the past 20 years, Sepragen Corporation has been a world leader in state-of-the art downstream purification products, where they help manufacture over 20+ FDA approved drugs in over 200 global installations.
Radial Flow Columns
In-Line Buffer Dilution/Buffer Making Systems
Inexpensive, fast Single-Use Resins
Radial Flow Chromatography Columns
From lab scale to cGMP production
Proven in over twenty clinically approved products
Key advantages over traditional axial columns:
From Lab Scale
Traditional Axial Columns
Radial Flow Columns
Single-Use Chromatography Systems with disposable flow path:
Dual Column Continuous Chromatography Platform with Integrated Buffer Blending/Making Capabilities
Dual Chromatography System – PD and Pilot chromatography system in one small footprint
Standard Chromatography Systems - All chromatography systems are 21CFR Part 11 Compliant
Custom Chromatography Systems
Custom projects include:
Increase Buffer Making Capacity without Increasing Tank Capacity
4X Higher Flow Rates than Competition
QS Packer is the world’s first automated packing system for packing its innovative Superflo, Radial Flow Columns.
The Packing Skid Enables:
The system takes the user through the various steps of:
Pneumatically driven diaphragm pumps and automated diaphragm slurry and buffer valves, column packing and running valve manifold, air removal device and sensors for measuring pressure, air, UV and conductivity.
The software enables either operator driven manual packing via a user friendly GUI or method driven automated packing once clear procedures are developed. Various packing protocols which include different flow rates, packing pressures for different columns and different resins can be stored in the QS Packer’s 21 CFR Pt11 compliant software. A salt, acetone or trace protein may be used to check bed integrity. The system software calculates the Asymmetry and HETP. Column packing batch reports are created and may be stored for review, comparison and retrieval.
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